ea0077p88 | Neuroendocrinology and Pituitary | SFEBES2021
Taiwo-Ola Dorcas
, Olanrewaju John
, Bejide Ronald
, Njideaka Temi
The hippocampus is majorly involved in memory formation. The insulin pathway regulates the level of GSK-3β, which is involved in the formation of amyloid beta and Tau. Allium sativumhas been shown to reduce amyloidogenesis and increase brain insulin sensitivity. 32 male Wistar rats were used in this experiment. They were grouped into 4, each with 8 rats. Group A (Sham), B (3 mg/kg of streptozotocin), group C (3 mg/kg of streptozotocin +300 mg/kg of Allium sat...